3- Subjects receiving drugs that were known to interfere with cardiac or respiratory Imatinib order functions such as β-blockers, vasodilators, and sympathomimetic and antihypertensive drugs. Subjects having history of chronic alcohol consumption,
chronic. 4- Subjects consuming tobacco in any form. 5- Subjects with hypertension (systolic blood pressure more than 140 mm of Hg and or diastolic blood pressure more than 90 mm of Hg) or obesity. Clinical Evaluation All participants were interviewed for assessing demographic information, health history, personal habits including alcohol consumption and smoking, physical activity as well as Rose questionnaire for angina and intermittent claudication. Inhibitors,research,lifescience,medical The presence of angina, possible myocardial infarction or intermittent claudication was Inhibitors,research,lifescience,medical especially assessed by using defined Rose questionnaire criteria.14 Direct patient interviews for a history of myocardial infarction were also employed. Subjects were also examined for pulse, blood pressure, height, weight, body-mass index. The systemic examination was included the examination of cardiovascular and respiratory system. Recording of Blood Pressure Both systolic and diastolic blood pressures were measured in supine position after a rest for about 5 minutes. At least two readings of five min interval were recorded. If a blood Inhibitors,research,lifescience,medical pressure of >140/90 mmHg was noted, a third reading was
obtained after 30 minutes. The lowest of the three measurements was taken as blood pressure. Recording of ECG Before recording of the ECG, the whole procedure was explained to the subject. The subject
was asked to relax in supine position for 30 minutes. The Inhibitors,research,lifescience,medical relaxed physical and mental state of the subject was confirmed. Then, a resting 12-lead ECG was recorded in supine position, in accordance with classical recommendations on the BPL 108 ECG machine. All electrocardiograms were recorded between 9.00 am to 12.00 noon in a calm atmosphere, at a Inhibitors,research,lifescience,medical room temperature varying from 27 to 30˚C. These ECGs were read and coded on the basis of Minnesota code criteria (table 1).14 Table 1: The prevalence of various electrocardiogram abnormalities in males and females participants Statistical Analysis The data were analyzed using Chi-square test. A P value of ≤0.05 was considered statistically significant. Results Carfilzomib The distribution of electrocardiographic abnormalities including left axis deviation, sinus bradycardia, ST-T wave abnormalities, bundle branch block, left ventricular hypertrophy, Q-QS pattern, ventricular premature beats, RVH and RAD are shown in descending order of frequency in table 2. We found that the total prevalence of ECG abnormalities in urban population of Solapur city was 38% (152/400). The prevalence of ECG abnormalities in males was significantly (P<0.001) higher than that in females. Table 2: The Minnesota Coding used to define electrocardiogram abnormalities The prevalence of ECG abnormalities in males (40%) was significantly (P<0.